CDS:PFLU_0024-0

Annotations
Annotations: 
This record has the following annotations.
TermNameDefinition
GO:0050661NADP bindingBinding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH. [GOC:ai]
GO:0019632shikimate metabolic processThe chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids. [GOC:sm, ISBN:0198547684]
GO:0009423chorismate biosynthetic process
GO:0009073aromatic amino acid family biosynthetic processThe chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). [GOC:go_curators]
GO:0008652cellular amino acid biosynthetic processThe chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. [ISBN:0198506732]
GO:0004764shikimate 3-dehydrogenase (NADP+) activityCatalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+. [EC:1.1.1.25]
Contact
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Cross Reference
Cross Reference: 
EMBL
  • AM181176
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EggNOGLoading content
GeneIDLoading content
HAMAPLoading content
InterProLoading content
KEGGLoading content
MPBAS00001Loading content
OrthoDBLoading content
PRIDELoading content
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UniPathway
  • UPA00053;UER00087
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Location on Map
Location on Map: 
MapPositionMap Description
This are no positions on any maps.
Properties
Pathway
PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. {ECO:0000256|ARBA:ARBA00004871, ECO:0000256|HAMAP-Rule:MF_00222}.
Similarity
  • SIMILARITY: Belongs to the shikimate dehydrogenase family. {ECO:0000256|HAMAP-Rule:MF_00222}.
  • fasta; with=UniProt:AROE_ECOLI (EMBL:U00096);Escherichia coli.; aroE; Shikimate dehydrogenase (EC1.1.1.25).; length=272; id 52.920%; ungapped id 53.903%;E()=1.2e-43; 274 aa overlap; query 1-272; subject 1-271
  • fasta; with=UniProt:AROE_PSEAE (EMBL:AE004442); Pseudomonas aeruginosa.; aroE; Shikimate dehydrogenase (EC 1.1.1.25).; length=274; id 73.529%; ungapped id 73.529%; E()=1.5e-70; 272 aa overlap; query 1-272; subject 1-272
Codon Start
1
Uniprot Annotation Score
3 out of 5
Ft Domain
DOMAIN 6..87; note:Shikimate_dh_N; evidence:ECO:0000259|Pfam:PF08501; DOMAIN 116..191; note:Shikimate_DH; evidence:ECO:0000259|Pfam:PF01488; DOMAIN 238..267; note:SDH_C; evidence:ECO:0000259|Pfam:PF18317
Gene
aroE
Product
  • Shikimate dehydrogenase (NADP(+)) (SDH) (EC 1.1.1.25)
  • shikimate dehydrogenase
Annotated Protein Regions
REGION 14..16; note:Shikimate binding; evidence:ECO:0000256|HAMAP-Rule:MF_00222
Uniprot Review Status
unreviewed
Protein Id
CAY46309.1
Frame
0
Inference
Inferred from homology
Confidence Level
2
Seqid
MPBAS00001
Locus Tag
PFLU_0024
Features
Active site (1); Binding site (8); Domain (3); Nucleotide binding (2); Region (1)
Protein Families
Shikimate dehydrogenase family
Publication
Publication: 
There are no publications associated with this record.
Relationship
Relationship: 
There are 0 relationships.
Relationships
There are no relationships
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Sequences
Sequence
No sequence is available.
Sequence Length
Sequence Checksum
d41d8cd98f00b204e9800998ecf8427e
Sequence Coordinates
MPBAS00001:26404..27222+
Summary
Resource Type
CDS
Accession
Organism
Name
CDS:PFLU_0024-0
Identifier
CDS:PFLU_0024-0
Is Analysis
No
Is Obsolete
No
Time Accessioned
Thursday, February 24, 2022 - 23:06
Time Last Modified
Thursday, February 24, 2022 - 23:06