CDS:PFLU_2556-0

Annotations
Contact
Cross Reference
Location on Map
Properties
Publication
Relationship
Sequences
Summary
Annotations
Annotations: 
This record has the following annotations.
TermNameDefinition
GO:1990961xenobiotic detoxification by transmembrane export across the plasma membraneA process that reduces or removes the toxicity of a xenobiotic by exporting it outside the cell. [PMID:28355133]
GO:0046677response to antibiotic
GO:0015562efflux transmembrane transporter activityEnables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane. [GOC:ai, GOC:mtg_transport, ISBN:0815340729]
GO:0008559ABC-type xenobiotic transporter activityCatalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out). [EC:7.6.2.2]
GO:0005887integral component of plasma membraneThe component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. [GOC:dos, GOC:go_curators]
GO:0005524ATP bindingBinding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
Contact
Contact: 
NameDescriptionType
There are no contacts available.
Cross Reference
Cross Reference: 
EMBL
  • AM181176
EggNOG
GeneID
InterPro
KEGG
MPBAS00001
OrthoDB
PRIDE
Pfam
Pubmed
RefSeq
STRING
SUPFAM
Location on Map
Location on Map: 
MapPositionMap Description
This are no positions on any maps.
Properties
Similarity
  • SIMILARITY: Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family. {ECO:0000256|HAMAP-Rule:MF_01720}.; SIMILARITY: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily. {ECO:0000256|ARBA:ARBA00005236}.
  • fasta; BAV2813; bavium; putative macrolide-specific ABC-type efflux carrier; length 655 aa; id=56.8%; ; E()=9.2e-124; 655 aa overlap; query 1-652 aa; subject 1-655 aa
  • fasta; BPSS0624; bpseudomallei; macrolide-specific ABC-type efflux carrier; length 653 aa; id=66.4%; ; E()=1.9e-148; 655 aa overlap; query 1-652 aa; subject 1-653 aa
  • fasta; Cj0607; cjejuni; ABC-type transmembrane transport protein; length 641 aa; id=43.2%; ; E()=9.9e-97; 650 aa overlap; query 5-652 aa; subject 1-641 aa
  • fasta; ECA0887; ecarotovora_atroseptica; macrolide-specific ABC-type efflux carrier; length 650 aa; id=56.3%; ; E()=8e-129; 652 aa overlap; query 1-652 aa; subject 1-650 aa
  • fasta; Ec042-0971; ecoli042; macrolide transport protein (ABC superfamily, atp_bind (N-terminal), membrane (C-terminal)); length 648 aa; id=57.8%; ; E()=2.8e-133; 654 aa overlap; query 4-652 aa; subject 3-648 aa
  • fasta; NMA0729; nmeningitidis_serogroupA_strainZ2491; putative ABC transporter ATP-binding protein; length 644 aa; id=54.0%; ; E()=4.5e-123; 648 aa overlap; query 5-652 aa; subject 3-644 aa
  • fasta; NMC0489; nmeningitidis_serogroupC_strainFAM18; putative ABC transporter ATP-binding protein; length 644 aa; id=54.0%; ; E()=8.8e-123; 648 aa overlap; query 5-652 aa; subject 3-644 aa
  • fasta; SBG0803; sbongori; conserved hypothetical ABC transporter; length 648 aa; id=56.6%; ; E()=1.9e-126; 648 aa overlap; query 5-652 aa; subject 4-648 aa
  • fasta; SDT0913; styphimuriumDT104; conserved hypothetical ABC transporter; length 648 aa; id=56.3%; ; E()=1.4e-125; 648 aa overlap; query 5-652 aa; subject 4-648 aa
  • fasta; SEN0850; senteritidisPT4; conserved hypothetical ABC transporter; length 648 aa; id=56.5%; ; E()=1e-127; 648 aa overlap; query 5-652 aa; subject 4-648 aa
  • fasta; STY0938; styphi; conserved hypothetical ABC transporter; length 648 aa; id=56.5%; ; E()=9.7e-126; 648 aa overlap; query 5-652 aa; subject 4-648 aa
  • fasta; YE1515; yenterocolitica; putative ABC transporter ATP-binding protein; length 649 aa; id=57.7%; ; E()=4.2e-127; 650 aa overlap; query 5-652 aa; subject 4-649 aa
  • fasta; YPO1365; ypestis; putative ABC transporter ATP-binding protein; length 649 aa; id=58.7%; ; E()=1.9e-130; 652 aa overlap; query 5-652 aa; subject 4-649 aa
Codon Start
1
Uniprot Annotation Score
3 out of 5
Note
; evidence=IEA; db_xref=bpseudomallei:BPSS0624; date=20060221; method=automatic:reciprocal fasta
Ft Domain
DOMAIN 5..277; note:MACB; evidence:ECO:0000259|PROSITE:PS51267; DOMAIN 6..244; note:ABC transporter; evidence:ECO:0000259|PROSITE:PS50893
Gene
PFLU_2556
Product
  • Macrolide export ATP-binding/permease protein MacB (EC 7.6.2.-)
  • macrolide-specific ABC-type efflux carrier
Ortholog
  • GeneDB_bavium:BAV2813
  • GeneDB_bpseudomallei:BPSS0624
  • GeneDB_cjejuni:Cj0607
  • GeneDB_ecarotovora_atroseptica:ECA0887
  • GeneDB_ecoli042:Ec042-0971
  • GeneDB_nmeningitidis_serogroupA_strainZ2491:NM A0729
  • GeneDB_nmeningitidis_serogroupC_strainFAM18:NM C0489
  • GeneDB_sbongori:SBG0803
  • GeneDB_senteritidisPT4:SEN0850
  • GeneDB_styphi:STY0938
  • GeneDB_styphimuriumDT104:SDT0913
  • GeneDB_yenterocolitica:YE1515
  • GeneDB_ypestis:YPO1365
Uniprot Review Status
unreviewed
Protein Id
CAY48791.1
Frame
0
Inference
Inferred from homology
Confidence Level
2
Seqid
MPBAS00001
Locus Tag
PFLU_2556
Features
Domain (2); Nucleotide binding (1); Transmembrane (3)
Protein Families
ABC transporter superfamily, Macrolide exporter (TC 3.A.1.122) family; ABC-4 integral membrane protein family, LolC/E subfamily
Primary Name
macB
Publication
Publication: 
There are no publications associated with this record.
Relationship
Relationship: 
There are 0 relationships.
Relationships
There are no relationships
Sequences
Sequence
No sequence is available.
Sequence Length
Sequence Checksum
d41d8cd98f00b204e9800998ecf8427e
Sequence Coordinates
MPBAS00001:2820371..2822329+
Summary
Resource Type
CDS
Accession
Organism
Pseudomonas fluorescens
Name
CDS:PFLU_2556-0
Identifier
CDS:PFLU_2556-0
Is Analysis
No
Is Obsolete
No
Time Accessioned
Thursday, February 24, 2022 - 23:06
Time Last Modified
Thursday, February 24, 2022 - 23:06